Antibiotic group tetracycline. Review and reviews, generic.

By | February 6, 2019

Best Place to Buy Tetracycline Online

Pills are coated 250 mg: 20, 30 or 40 pcs.tetracycline caps
Clinico-pharmacological group:

Tetracycline group antibiotic
Release form, composition and packaging
pills, coated 1 tab.
tetracycline hydrochloride 250 mg

10 pieces. – Contour cell packages (2) – cardboard packs.
10 pieces. – contour cell packages (3) – cardboard packs.
10 pieces. – Contour cell packages (4) – cardboard packs.
20 pcs. – polymer cans (1) – cardboard packs.
40 pcs. – polymer cans (1) – cardboard packs.

Description of the active components of the drug “Tetracycline”

Pharmachologic effect: Broad-spectrum antibiotic. It has a bacteriostatic effect due to the suppression of protein synthesis of pathogens.

Gram StainActive against aerobic gram-positive bacteria: Staphylococcus spp. (including penicillinase producing strains), Streptococcus spp .; Gram-negative bacteria: Neisseria gonorrhoeae, Bordetella pertussis, Enterobacter spp., Escherichia coli, Klebsiella spp., Salmonella spp., Shigella spp .; anaerobic bacteria: Clostridium spp.

Also active in relation to Rickettsia spp., Chlamydia spp., Mycoplasma spp., Spirochaetaceae.

Pseudomonas aeruginosa, Proteus spp., Serratia spp., Most strains of Bacteroides fragilis, most of the fungi, small viruses are resistant to tetracycline.

Indications
Infectious and inflammatory diseases caused by microorganisms sensitive to tetracycline, incl. pneumonia, bronchitis, empyema, angina, cholecystitis, pyelonephritis, intestinal infections, endocarditis, endometritis, prostatitis, syphilis, gonorrhea, brucellosis, rickettsioses, purulent infections of soft tissues, osteomyelitis; trachoma, conjunctivitis, blepharitis; acne

Prevention of postoperative infections.

Dosing regimen
Inside adults – 250-500 mg every 6 hours. Children over 8 years old – 25-50 mg / kg every 6 hours.

Outwardly used several times a day, if necessary, impose a weak bandage.

Local – 3-5 times / day.

The maximum daily intake for adults when administered orally is 4 g.

Side effect
On the part of the digestive system: nausea, vomiting, anorexia, abdominal pain, diarrhea, constipation, dry mouth, glossitis, discoloration of the tongue, esophagitis, transient increase in liver transaminase, alkaline phosphatase, bilirubin concentration, residual nitrogen.

From the hematopoietic system: neutropenia, thrombocytopenia, hemolytic anemia.

  1. Allergic reactions: skin rash, itching, eosinophilia, angioedema.
  2. Dermatological reactions: photosensitivity.
  3. Effects due to chemotherapeutic action: candidal stomatitis, vulvovaginal candidiasis, intestinal dysbacteriosis.
  4. Local reactions: pain at the injection site.
  5. Others: Vitamin B hypovitaminosis.
    Contraindications

Hepatic insufficiency, leukopenia, mycoses, children under 8 years of age, pregnancy, lactation (breastfeeding), increased tetracycline sensitivity.
Pregnancy and lactation

Tetracycline is contraindicated during pregnancy and lactation.

It penetrates the placental barrier. May cause long-term discoloration of the teeth, enamel hypoplasia, suppression of the growth of the bones of the fetal skeleton. In addition, tetracycline may be the cause of the development of fatty infiltration of the liver.
Application for violations of the liver

Contraindicated in liver failure.

Application for children:

Contraindicated in children up to 8 years. The use of tetracycline in children during the development of teeth can lead to an irreversible change in their color.

special instructions
With prolonged use, it is necessary to periodically monitor the function of the kidneys, liver, blood-forming organs.

The use of tetracycline in children during the development of teeth can lead to an irreversible change in their color.

During treatment, vitamins of group B, K, brewer’s yeast should be used to prevent hypovitaminosis.

Tetracycline should not be taken simultaneously with milk and other dairy products, since at the same time absorption of an antibiotic is broken.

Drug interaction
Preparations containing metal ions (antacids, preparations containing iron, magnesium, calcium) form inactive chelates with tetracycline, and therefore their simultaneous use should be avoided.

It is necessary to avoid combinations with penicillins, cephalosporins, which have a bactericidal effect and which are antagonists of bacteriostatic antibiotics (including tetracycline).

With simultaneous use of tetracycline with retinol may develop intracranial hypertension.

At simultaneous use with kolestiramin or kolestipol violation of absorption of tetracycline is noted.

Drug interaction

Preparations containing metal ions (antacids, preparations containing iron, magnesium, calcium) form inactive chelates with tetracycline, and therefore their simultaneous use should be avoided.

It is necessary to avoid combinations with penicillins, cephalosporins, which have a bactericidal effect and which are antagonists of bacteriostatic antibiotics (including tetracycline).

With simultaneous use of tetracycline with retinol may develop intracranial hypertension.

At simultaneous use with kolestiramin or kolestipol violation of absorption of tetracycline is noted.
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